Order Priligy Canada– Medical Informatics Laboratory

Order Priligy Canada - Medical Informatics Laboratory

Overview

Priligy (dapoxetine) is a potent, selective, rapid-acting serotonin reuptake inhibitor (SSRI) that also modulates norepinephrine and dopamine reuptake. Its mechanism centers on inhibiting neuronal serotonin reuptake, thereby amplifying serotonin's effect on sympathetic nervous system receptors responsible for ejaculatory control. Peak plasma concentrations occur approximately two hours post-administration.

Product Information

Priligy active ingredient is dapoxetine, classified as a selective serotonin reuptake inhibitor (SSRI) and urological agent. It extends time to ejaculation and enhances ejaculatory control, alleviating distress associated with premature ejaculation. Approved for men aged 18-64 experiencing premature ejaculation (PE).

Pricing & Offers

All orders include package delivery insurance and a 10% discount on future purchases.

Strength	Quantity	Price	Price/Pill	Action
30mg	30 pills	$51.09	$1.70	add to cart
	90 pills	$100.14	$1.11	add to cart
	120 pills	$124.66	$1.04	add to cart
60mg	20 pills	$43.24	$2.16	add to cart
	30 pills	$54.74	$1.82	add to cart
	60 pills	$89.25	$1.49	add to cart
90mg	10 pills	$49.48	$4.95	add to cart
	30 pills	$105.80	$3.53	add to cart
	120 pills	$359.22	$2.99	add to cart

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Clinical Context

Pharmacological modulation of ejaculation represents a paradigm shift beyond psychosexual PE models. While SSRIs revolutionized PE treatment, methodological flaws limit the reliability of early studies. Meta-analyses indicate only 14.4% efficacy across PE medications, with dapoxetine demonstrating superior reliability. Note: PE symptoms often recur post-treatment discontinuation. Optimal outcomes typically involve 60-day pharmacotherapy combined with couplesвЂ™ sexual therapy to establish sustained ejaculatory control.

Mechanism of Action

As the sole approved on-demand PE treatment for men 18-64, Priligy rapid-acting SSRI profile enables dosing 1вЂ“3 hours pre-intercourse (max once daily). It achieves peak plasma concentration within ~1 hour, undergoes hepatic metabolism (yielding desmethyl/dimethyl metabolites), and renal excretionв-minimizing accumulation. Pharmacokinetics are dose-dependent but unaffected by food/alcohol. Contraindicated in hepatic/renal impairment, with CYP450 inhibitors (e.g., ketoconazole, ritonavir), or concurrent serotonergic drugs. Use cautiously in cardiovascular disease. Notably, no interactions occur with phosphodiesterase-5 inhibitors.

Indications

Priligy is indicated for men experiencing:

Persistent intravaginal ejaculation latency <2 minutes
Chronic/recurrent ejaculation with minimal stimulation
PE-related personal/interpersonal distress
Inability to delay ejaculation
Documented PE episodes within the past 6 months

Contraindications:

Hypersensitivity to components
Moderate/severe hepatic dysfunction
Mania, hypomania, severe depression, bipolar disorder
Cardiac conditions (failure, block, CAD, valvular disease)
Concomitant serotonergic agents

Dosage

Starting dose: 30mg taken 1вЂ“3 hours before intercourse
Adjustment: May increase to 60mg based on efficacy/tolerance
Frequency: Not for daily use; limit to on-demand dosing
Reassessment: Evaluate risk-benefit after 6 doses

Side Effects

Common:

Dizziness, headache, nausea
Anxiety, agitation, insomnia, reduced libido
Somnolence, blurred vision, tinnitus, vomiting, hyperhidrosis

Less Common:

Depression, euphoria, bruxism, syncope, dysgeusia
Tachycardia, hypertension, diarrhea, erectile dysfunction

Consult the package leaflet or healthcare provider for full safety information. Misuse poses serious health risks.

Conclusion

Priligy demonstrates proven efficacy in PE management, extending intercourse duration by ~3-4 minutes with favorable tolerability. Its on-demand profile offers flexibility unmatched by traditional SSRIs. While psychotherapy remains an alternative/complementary option, dapoxetine provides a clinically validated pharmacological solution accessible across medical specialties treating PE.